Imagine stepping into a high-stakes meeting, not with anxiety, but with laser-focused confidence. What if you could optimize your brain to be at its best before every crucial conversation?

That’s exactly what David J.P. Phillips, author of High on Life, shared in our latest episode of Think Deeply, Speak Simply with Prezent CEO Rajat Mishra. With over 20 years of experience studying human behavior, communication, and storytelling, and three viral TED Talks under his belt, David shared the science behind mental optimization and how small adjustments can completely change the way we show up in meetings, presentations, and even everyday conversations.

Key Takeaways

1. Your mind is your greatest asset—train it well. The way you talk to yourself shapes how others see you. Upgrade your self-talk, and you'll naturally command more presence.
2. Turn anxiety into confidence with the ‘Angel’s Cocktail.’ A simple mix of three neurotransmitters can flip nerves into power. Master this formula and own any room.
3. Facts tell, but stories sell—activate your audience’s brain. PowerPoint engages 20% of the brain, but a great story lights it all up. If you want to be memorable, tell a story.
4. Your virtual setup speaks before you do. Bad lighting and poor audio make you seem less credible. Upgrade your setup, and people will take you seriously.
5. The story you tell yourself is the most important one. Walk in believing you belong, and your audience will believe it too. Confidence starts in your mind.

Here’s a deeper dive: 

Your internal communication shapes your external impact

For years, David coached top leaders on public speaking—teaching them how to use body language, storytelling, and voice control to captivate their audience. But he discovered something even more crucial along the way:

“The best salesperson in the room can master mirroring, facial expressions, and micro-expressions,” he says. “But if their internal communication sucks, the audience will feel it.”

David realized this truth firsthand. After spending years helping leaders refine their external communication, he realized that he had been unknowingly depressed for 15 years, undermining his own internal dialogue.

 A random moment on a bridge with his wife changed everything. He actually felt happy. “It’s rare for adults to feel a completely new emotion, but it happened to me,” he recalls. That moment of clarity set him on a path to understanding how to rewire our minds for happiness, confidence, and success – and he’s been sharing what he discovered ever since.

Because the most successful communicators don’t just master how they speak. They master how they think.

The Angel’s Cocktail: A brain hack for instant confidence

Before stepping onto a stage or into a big meeting, most people unknowingly sabotage themselves. David calls it the “Devil’s Cocktail”—a mix of self-doubt, nervous pacing, and shallow breathing that triggers cortisol and adrenaline, making us anxious and ineffective.

Instead, he recommends preparing an “Angel’s Cocktail.”And no, this is not a fruity cocktail it’s a powerful mix of neurotransmitters that boost confidence and focus. Here’s how to make it:

✅ Increase Testosterone: This hormone boosts confidence and presence. “If you can increase your testosterone before a presentation, you are more likely to be listened to,” David explains. Stand tall, breathe deeply, and listen to powerful music that makes you feel unstoppable.

✅ Boost Oxytocin: This “connection hormone” makes you more present and engaging. “Spend two minutes looking at a picture of a loved one before a big meeting,” David advises. “It will make you more human, more caring, and your audience will feel it.”

✅ Raise GABA Levels: GABA is the brain’s natural ‘brake pedal’—it calms the mind. Meditation and slow, intentional breathing increase GABA, reducing stress and promoting clarity.

“When you combine testosterone for confidence, oxytocin for warmth, and GABA for calmness, you become invincible and loving—the most powerful combination,” says David.

Use storytelling to make your presentations memorable and engaging

Most corporate presentations are bullet points on slides—logical, but lifeless. David explains why storytelling is the secret weapon of great communicators.

“When you tell a story, so many parts of the brain light up—it’s like a Christmas tree,” he explains. “The audience feels your words, and they remember your message.”

Compare that with a dry PowerPoint slide. “Only the visual and language centers of the brain activate. It’s like lighting up just 20% of a Christmas tree.”

His advice? If you’re giving a presentation, make sure to include one story every 10 minutes. It engages the audience and makes your message unforgettable.

Don’t sabotage yourself — take virtual meetings seriously

David is on a mission to fix what’s broken in virtual meetings. “People don’t take them seriously,” he says. “And that’s why remote work is struggling.”

According to him, Google got it right. “When COVID hit, they sent every top manager a professional microphone, camera, and lighting setup. Their meetings felt polished, engaging,” he says.

Meanwhile, other major companies stuck with bad webcams and laptop mics—making their leaders seem less credible and less engaging. The result? Lower engagement, weaker influence, and a disconnect between leaders and their teams.

His advice? If you’re in a leadership position, invest in a high-quality microphone, camera, and proper lighting. It’s a small upgrade with a massive impact on how you’re perceived—and how effectively you lead.

Your most important story is the one you tell yourself

The biggest takeaway from this episode? The stories we tell ourselves define how we show up in the world. “What we repeat, we become,” David says. If we constantly tell ourselves we’re bad presenters, that meetings are stressful, or that we don’t have the confidence to speak up, our brain will believe it.

Instead, train your brain for confidence. Create your Angel’s Cocktail, optimize your storytelling, and show up to every meeting like the best version of yourself.

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